GGO Vergunningendatabase

IM-MV 18-003_004 UMCG Study of Adeno-Associated Virus (AAV) Serotype 8 (AAV8)-Mediated Gene Transfer of Glucose-6-Phosphatase (G6Pase) in subjects with Glycogen Storage Disease Type la (GSDIa) 21-12-2021 Vergunning verleend
IM-MV 19-024_003 Stichting Radboud Universiteit EXPLORE: A Phase II, masked multicentre, randomised study to evaluate the safety and efficacy of two doses of GT005 administered as a single subretinal injection in subjects with geographic atrophy secondary to age-related macular degeneration 30-12-2021 Vergunning verleend
IM-MV 21-004_000 Stichting Radboud Universiteit Open-Label, Single Ascending Dose Study to Evaluate the Safety, Tolerability, and Efficacy of EDIT-101 in Adult and Pediatric Participants with Leber Congenital Amaurosis Type 10 (LCA10), with Centrosomal Protein 290 (CEP290)-Related Retinal Degeneration Caused by a Compound Heterozygous or Homozygous Mutation Involving c.2991+1655A>G in Intron 26 (IVS26) of the CEP290 Gene (“LCA10-IVS26”) 16-12-2021 Vergunning verleend
IM-MV 21-024_000 Het Nederlands Kanker Instituut Application of nuclease-mediated TCR gene editing of an autologous T cell product targeting a limited number of tumor-specific neoantigens for the treatment of advanced solid tumors 10-12-2021 Vergunning verleend